New England Journal of Medicine

New England Journal of Medicine

Published: February 10, 2025

A Noninvasive Test to Determine Paternity in Pregnancy

Publications

Lancet

A non-invasive test for prenatal diagnosis based on fetal DNA present in maternal blood: a preliminary study Use of free fetal DNA to diagnose fetal chromosomal abnormalities has been hindered by the inability to distinguish fetal DNA from maternal DNA. Our aim was to...

JAMA

Methods to Increase the Percentage of Free Fetal DNA Recovered From the Maternal Circulation Noninvasive prenatal diagnostic tests using free fetal DNA provide an alternative to invasive tests and their attendant risks; however, free fetal DNA exists in the maternal...

News

WUSA9: Early Paternity Test Has Potential to Help Rape Victims

WASHINGTON, D.C. (WUSA) -- Knowing the paternity of a child is a piece of information that many take for granted. But for some, it is a terrible burden of uncertainty. Thousands of rape victims become pregnant every year, and not knowing who the father of their child...

The New York Times: Before Birth Dad’s ID

It is an uncomfortable question that, in today’s world, is often asked by expectant mothers who had more than one male partner at the time they became pregnant. Who is the father? Read Full Story at NY Times

WebMD: New Earlier, Noninvasive Paternity Test Developed

Experts Say the Test Has Important Medical, Legal Applications May 2, 2012 -- Researchers say they've found a way to identify the father of a baby as early as the eighth week of pregnancy. The new method, reported in the New England Journal of Medicine, uses fetal DNA...

The Prosecution of Michael Roseboro

In 2008, our Prenatal DNA Paternity technology was used in the prosecution of the Michael Roseboro murder trial of Lancaster County, Pennsylvania. Click the link to the right to see a description of how our Non-invasive Prenatal DNA Paternity Test was used in this...

CNN Fortune Small Business: A Better Prenatal Test

Life was proceeding as planned for Ravinder Dhallan, or so it seemed. Having earned doctorates in medicine and biomedical engineering at Johns Hopkins University, he had just started a radiation oncology residency at Massachusetts General Hospital. On the home front...

Experimental Prenatal Test Helps Spot Birth Defects

It's noninvasive, but don't expect to see it on the market soon By Amanda GardnerHealthDay Reporter  FRIDAY, Feb. 2 (HealthDay News) -- A new, noninvasive method of prenatal testing may one day help to detect birth defects in unborn babies. But it'll be a while...

MIT Technology Review: A Simpler Test for Detecting Down’s Syndrome

A new blood test uses scraps of fetal DNA to piece together a prenatal diagnosis. In January, the American College of Obstetricians and Gynecologists recommended that all pregnant women have access to Down’s syndrome screening, which in the past was advised only for...

REUTERS: New Down’s test eliminates miscarriage risk

LONDON (Reuters) - A new non-invasive test that examines fetal DNA can pick up genetic abnormalities such as Down’s syndrome, researchers said on Friday. Unlike more intrusive tests that may raise the risk of miscarriage, the new diagnostic tool developed by the US...